VISDB Viral Integration Site DataBase

VIS ID

TVIS42001094

Fusion event

EBV-ABCC4 integration

Validated

No

Detection method

GenCap Enrichment+NGS

Data source

Curated

Sample type

Disease

Gastric carcinoma (GC)

Quality evaluation

Normal

Reported year

2015

PubMed ID

Virus name

EBV

Reference genome

Start

82916

Orient

-

Integrated sequence

TGTTCACATGTGTCAGGATGACGAGTTTCCGGATCTACAAGATCCTCCAGATGAGGCCTAAGCAAAGGTGTAGAAGTGTGTCCCCCTCCATTCCACCCAC| |TGATAATACGCCCGACAATAAAGTTGATGATATTGAATTCCACACCTGCTTGTGTTTGTGATTTTATTTCATATTCCATGAGAGAGACCTCGCATATTTG

Chromosome

chr13

Cytoband

q32.1

Reference genome

Start

End

95919044/95266790 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-125b-5p ; hsa-mir-155-5p ; hsa-mir-1-3p ; hsa-mir-16-5p ; hsa-mir-324-5p ; hsa-mir-23b-3p ; hsa-mir-3924 ; hsa-mir-98-3p ; hsa-let-7f-1-3p ; hsa-let-7b-3p ; hsa-let-7a-3p ; hsa-mir-8064 ; hsa-mir-7853-5p ; hsa-mir-105-5p ; hsa-mir-4666a-3p ; hsa-mir-381-3p ; hsa-mir-300 ; hsa-mir-1277-5p ; hsa-mir-7-2-3p ; hsa-mir-7-1-3p

Nearest miRNA

hsa-mir-1297/Upstream/2776570; hsa-mir-1267/Downstream/1160439;

Nearest TSS

Nearest CpG islands

None/Target, chr13-CpG: 551/Upstream/263639, chr13-CpG: 120/Downstream/34216

Upstream sequence

ccttagaatctaacacagcacctggcacttagtagttatccaatcaacaatgtttgtgaaatgaaagaaGAATGAGaagatgaaaagatgagaggaagga

Downstream sequence

agggagggagagaggaaagaaagaggaagaaaagGGTGGTGATTGGTTACTTGTAAGACAGTTCATTCACTGGAAACTTATGAATTATTTATTCATTATT