Basic Information
VIS ID
TVIS42001100
Fusion event
EBV-chr18:q22.1 integration
Validated
No
Detection method
GenCap Enrichment+NGS
Data source
Curated
Sample type
Tumor
Disease
Hodgkin lymphoma (HL)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25355872
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
122756
Orient
-
Integrated sequence
TAGGCCAGGGTCTGGGCCACGTGCTGAAAGTCCACCCCGAGGCCGCACATGTGGGCATTGGTGCAGGTTGGGAGGAAAACGTAGTAAAAGATCTTTTCCA| |GCACATCCGCATGCCCCTCATCTACATAAGGGCCTAGGTGCAGACGGAAATCGTGGTCGTGGTCTCCGTTAACCCGGTAGCCGTACAAGGCCACAAATTG
Host Sequence
Chromosome
chr18
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
63712264/66045028 (Hg38)
End
63712264/66045028 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1-2/Upstream/7593870; hsa-mir-5011/Downstream/1036556;
Nearest TSS
ENST00000575820/Upstream/124086; ENST00000581951/Downstream/527143;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/293624, chr18-CpG: 83/Downstream/1470972
Upstream sequence
acataaaagaaacaacccaattttcaaatgggcaaagtacttgaatagacatttttctccaaaagatgctcaacattatcagtcaataaggaaacacaaa
Downstream sequence
TACATGTGAATAGGCAAAACTGTAGAGAAAATAACTGGAATTCATAACTACCTTTAAATCAATAAAACAAAAATAATGAAGTGCTTACTTTTTTGCTTTT
Reference
Cao, S., et al.High-throughput RNA sequencing-based virome analysis of 50 lymphoma cell lines from the Cancer Cell Line Encyclopedia project. J Virol,2015, 89(1): 713-729.
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