Basic Information
VIS ID
TVIS42001101
Fusion event
EBV-chr2:p16.1 integration
Validated
No
Detection method
GenCap Enrichment+NGS
Data source
Curated
Sample type
Tumor
Disease
Hodgkin lymphoma (HL)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25355872
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
9957
Orient
+
Integrated sequence
TCTCTGCTAGAGGACTTTAAGGGCTACCTTGGATGCCAGGCCCTGTCAGAAATGATCCAATTCTACCTGGAGGAAGTCATGCCACAGGCTGAAAACCAGG| |ACCCTGAAGCCAAAGACCATGTCAATTCTTTGGGTGAAAATCTAAAGACCCTACGGCTCCGCCTGCGCAGGTGCCACAGGTTCCTGCCGTGTGAGAACAA
Host Sequence
Chromosome
chr2
Cytoband
p16.1
Reference genome
GRCh37/hg19
Start
60255134/60027999 (Hg38)
End
60255134/60027999 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA2S
Nearest miRNA
hsa-mir-1301/Upstream/4027204; hsa-mir-10b/Downstream/359363;
Nearest TSS
ENST00000437798/Upstream/294603; ENST00000444873/Downstream/72201;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/1599022, chr2-CpG: 103/Downstream/432688
Upstream sequence
GAAACAAGCCTAATGAGTCCTTTTGGGGTTTACAGAAGCATTCAAAAACTTGGAAGGAACAAGAGGCAGTAAACTGATGGATGGTCCCTGTATACGGAGG
Downstream sequence
ACTGTTTTCCATCCCTAAAGCATCGAATCCTGATTTCTGTTTTTGGTGTGTTTATCTGTTAGGCCCTTGCAGAGGGAATAGTTTTCATTTAAGGGGAAAA
Reference
Cao, S., et al.High-throughput RNA sequencing-based virome analysis of 50 lymphoma cell lines from the Cancer Cell Line Encyclopedia project. J Virol,2015, 89(1): 713-729.
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