Basic Information
VIS ID
TVIS42001102
Fusion event
EBV-chr20:p12.3 integration
Validated
No
Detection method
GenCap Enrichment+NGS
Data source
Curated
Sample type
Tumor
Disease
Hodgkin lymphoma (HL)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25355872
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
98547
Orient
+
Integrated sequence
GTTTTCTCCCCCAGATCACGGCTGTCTAGACGCGTGGGCCTCCCAGGGGGTGTTGCTACTCAACACCATCCTGACCGTGCAAAAGGGCAAGCCCGGCTCG| |CACGCAGACATTGGCTGGGCGTGGTTTACTGACCACGTAATTTCATTGCTCTCTGAGCGGTTAAAAGCGTGCGTGTTTATGCTGTGGGGTGCGAAGGCGG
Host Sequence
Chromosome
chr20
Cytoband
p12.3
Reference genome
GRCh37/hg19
Start
7411633/7430986 (Hg38)
End
7411633/7430986 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-103a-2/Upstream/59294; hsa-mir-1-1/Downstream/3218650;
Nearest TSS
ENST00000382410/Upstream/83519; ENST00000607924/Downstream/509488;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/660676, chr20-CpG: 96/Downstream/588156
Upstream sequence
taatatgaggtcttagaagaaAATCCACCATGTTAACAGTAAGGAAAGTGATAGCCTGGATACCGTGAAAAGTACAATTTTCAAacacacacacacacac
Downstream sequence
aggtttaatcataagattatagacccctggctctcccaatatcttaccaacaaattggggctccaggataataagagtggactgaaattgcaagagttgc
Reference
Cao, S., et al.High-throughput RNA sequencing-based virome analysis of 50 lymphoma cell lines from the Cancer Cell Line Encyclopedia project. J Virol,2015, 89(1): 713-729.
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