Basic Information
VIS ID
TVIS42001104
Fusion event
EBV-chr18:q22.3 integration
Validated
No
Detection method
GenCap Enrichment+NGS
Data source
Curated
Sample type
Tumor
Disease
Hodgkin lymphoma (HL)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25355872
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
103523
Orient
-
Integrated sequence
TGATAATCAGGGGCAGCGTCTCTACGTCAGATACTCGTCAGACACGATCTCTATATTATTGGGCCCCTTCACCTATCTGGTGGCAGAGCTTTCACCGGTG| |GAACTCGTGACAGATGTCTACGCCACCCTAGGCATCGTGGAGATCATCGACGAGCTCTACCGGAGCAGTCGCCTGGCCATCTACATCGAGGACCTCGGTC
Host Sequence
Chromosome
chr18
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
69861152/72193917 (Hg38)
End
69861152/72193917 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1-2/Upstream/5112231; hsa-mir-548av/Downstream/659404;
Nearest TSS
ENST00000575820/Upstream/249340; ENST00000578967/Downstream/346381;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/1763057, chr18-CpG: 225/Downstream/347822
Upstream sequence
GTATGAGATGGAATACAGCCATGCTTCAAAGACTATAAAATCAGATAAAAATTATAGTAAGTTTCATAAGTTTTTCAAAGGTTAAAAATGACTGGAAAGT
Downstream sequence
gatattttttcatggcatgtaaagaagtcttttcctacccccaaatcataaatacatatttttctatgcttcctagaaatgtaatagtttgggatttctg
Reference
Cao, S., et al.High-throughput RNA sequencing-based virome analysis of 50 lymphoma cell lines from the Cancer Cell Line Encyclopedia project. J Virol,2015, 89(1): 713-729.
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