Basic Information
VIS ID
TVIS42001105
Fusion event
EBV-chr8:q11.23 integration
Validated
No
Detection method
GenCap Enrichment+NGS
Data source
Curated
Sample type
Tumor
Disease
Hodgkin lymphoma (HL)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25355872
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
94134
Orient
+
Integrated sequence
TCGGTTATTTTGGTTCCTGAACATCTGGCTGGGGCATTAACTAAGCTTATGAGCGATTTTATCACAGGACAAGATGTCACTCTTTCTGGAGGAAATATTG| |CAGTCAAAATTCGCGATGCTATAAACCAGACCCCCGGGGGTGGTGATGTAGCTATACTTTCTTCCCTGTTTGCTTTATGGAATGCCCTCCCAACATCTGG
Host Sequence
Chromosome
chr8
Cytoband
q11.23
Reference genome
GRCh37/hg19
Start
53797899/52885339 (Hg38)
End
53797899/52885339 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-124-1/Upstream/9989064; hsa-mir-10400/Downstream/8829449;
Nearest TSS
ENST00000518652/Upstream/139496; ENST00000331251/Downstream/53092;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/170398, chr8-CpG: 235/Downstream/53802
Upstream sequence
ATCAGCTAAGTTTTTTAAATCAAAGTAAAAGGAATCAGAATCTTGATGTCAGTCTAGCCTGTACCTGACCTGCAAACTCCCTAAAAAGGAAAAAAAAAAA
Downstream sequence
actgtcttgattactgtaggtttatagtaagttttaaaatctggcttaagtttaaaatctgactcttctaactgcattgttctgtttccagctttttctg
Reference
Cao, S., et al.High-throughput RNA sequencing-based virome analysis of 50 lymphoma cell lines from the Cancer Cell Line Encyclopedia project. J Virol,2015, 89(1): 713-729.
Curate