VISDB Viral Integration Site DataBase

VIS ID

TVIS42001106

Fusion event

EBV-SLC25A42 integration

Validated

No

Detection method

GenCap Enrichment+NGS

Data source

Curated

Sample type

Disease

NK/T cell lymphoma (NKL)

Quality evaluation

Normal

Reported year

2015

PubMed ID

Virus name

EBV

Reference genome

Start

139023

Orient

+

Integrated sequence

GTAGGGGCCTCCACCTAGGTGCTTTGTTAATCTTTAGTGGGAACTAGTGGGAGTGCTGTGCCTCGGGTACCCCTATCCTATAGGTCCTACCGGAGCTCCT| |TGTCTTGATAATCCCTGTAAACACACACCACCTAAGAACAAGGCATTGTTAACCTTTGGTGGAACCTAGTGTTAGTGTTGTGCTGTAAATAAGTGTCCAG

Chromosome

chr19

Cytoband

p13.11

Reference genome

Start

End

19198954/19088145 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-375 ; hsa-mir-4433b-5p ; hsa-mir-1260b ; hsa-mir-1260a ; hsa-mir-532-3p ; hsa-mir-1224-3p ; hsa-mir-96-3p ; hsa-mir-2681-3p ; hsa-mir-5684 ; hsa-mir-6511b-3p ; hsa-mir-6511a-3p ; hsa-mir-6750-3p ; hsa-mir-551b-5p

Nearest miRNA

hsa-mir-10395/Upstream/701511; hsa-let-7e/Downstream/346918;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/23959, chr19-CpG: 52/Downstream/22242

Upstream sequence

tcctcctgaagtttacactgtggtgagggaaacagcaagaagtcaataagtagaaagtggatcaaatagagataaatgcatccaagaaagataaagcaag

Downstream sequence

TTTCTAAGGAACGGTTCCAGACCCCACCCCAGCCCTGCATATAAATCTGATCTTCAAtttttttttttttttttttttgagacaaagtctcactctgtca