VISDB Viral Integration Site DataBase

VIS ID

TVIS42001107

Fusion event

EBV-CRIM1 integration

Validated

No

Detection method

GenCap Enrichment+NGS

Data source

Curated

Sample type

Disease

NK/T cell lymphoma (NKL)

Quality evaluation

Normal

Reported year

2015

PubMed ID

Virus name

EBV

Reference genome

Start

162071

Orient

-

Integrated sequence

AGTTGTGCCACAGGTACAGGCTTGAGAGCTTAGTGTCCGGGAATAGGGTCTTGTGGTAGGTGTTGAGGAATTTCATGTAGGGCCCGTTGATGATGTAGTT| |CTCCCTCCTGGTAGTGGACTTGATGAAGCTGTTCTGGAGGGCGGCATTCTCCCCCGTGAAGACCACCCTGTTCTTGATCTTGATGTTCCTGGGGCACAGC

Chromosome

chr2

Cytoband

p22.2

Reference genome

Start

End

36761122/36533979 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-375 ; hsa-mir-26b-5p ; hsa-mir-455-3p ; hsa-mir-92b-3p ; hsa-mir-193b-5p ; hsa-mir-15b-5p ; hsa-mir-583 ; hsa-mir-302f ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-190a-3p ; hsa-mir-195-5p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-545-3p ; hsa-mir-568 ; hsa-mir-548e-5p ; hsa-mir-548p ; hsa-mir-6838-5p ; hsa-mir-18a-5p ; hsa-mir-18b-5p ; hsa-mir-4735-3p ; hsa-mir-3924 ; hsa-mir-656-3p ; hsa-mir-5011-5p ; hsa-mir-1277-5p ; hsa-mir-6079 ; hsa-mir-6077 ; hsa-mir-7-5p ; hsa-mir-129-5p ; hsa-mir-8055 ; hsa-mir-337-3p ; hsa-mir-153-5p ; hsa-mir-1250-3p ; hsa-mir-483-3p ; hsa-mir-1276 ; hsa-mir-4311 ; hsa-mir-4263 ; hsa-mir-487b-5p ; hsa-mir-487a-5p ; hsa-mir-8074 ; hsa-mir-876-3p ; hsa-mir-885-3p ; hsa-mir-4774-5p ; hsa-mir-4490 ; hsa-mir-4521 ; hsa-mir-183-5p ; hsa-mir-5584-3p ; hsa-mir-6874-3p ; hsa-mir-148b-5p ; hsa-mir-3168 ; hsa-mir-223-5p ; hsa-mir-4789-5p ; hsa-mir-511-3p ; hsa-mir-4783-5p ; hsa-mir-4789-3p ; hsa-mir-8485 ; hsa-mir-377-3p ; hsa-mir-3124-3p ; hsa-mir-342-3p

Nearest miRNA

hsa-mir-1301/Upstream/1062493; hsa-mir-10b/Downstream/10843696;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/176140, chr2-CpG: 56/Downstream/63670

Upstream sequence

AAATAACAGTACATGTCACATTAAGAAATAGATATTAATAAGGAATTTTACAAGAAAACAGCCACAGTAGGCTTCAATAGGGTGCAGCCTTCTGATGACA

Downstream sequence

gagagagggggaaggaaggaaggaaggaaaggagggagggagggtgaaaaggagagaaggaaggacagagggagaaggaaggaaggtgagggagtgggaa