VISDB Viral Integration Site DataBase

VIS ID

TVIS42001116

Fusion event

EBV-TNFAIP3 integration

Validated

Yes

Detection method

Sanger sequencing

Data source

Curated

Sample type

Disease

Nasopharyngeal carcinoma (NPC)

Quality evaluation

Perfect

Reported year

2015

PubMed ID

Virus name

EBV

Reference genome

Start

53442

Orient

-

Integrated sequence

GCGGTCTCGTAAAAAGCCAGGAAACTCTGCTTGGCCGAGGCATAGCGCAGCAGCTTGTCCTTGAGGAGGGCATACTGGGAGCCAGCCGAGGCCCCAAGCG| |CCAGGCCCCTGGCAGCCTCCACCACGATCTTGAGCTGGCGCGGGTCGGTGTGGCCCCTGGCCTGGGTGACCAGATCCTGCAGCGTTCCCTGCAGCTGGGA

Chromosome

chr6

Cytoband

q23.3

Reference genome

Start

End

138199528/137878391 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-21-5p ; hsa-mir-29a-3p ; hsa-mir-125a-5p ; hsa-mir-125b-5p ; hsa-mir-26b-5p ; hsa-mir-24-3p ; hsa-mir-374a-5p ; hsa-mir-4709-3p ; hsa-mir-3185 ; hsa-mir-4635 ; hsa-mir-4729 ; hsa-mir-5582-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-573 ; hsa-mir-3616-5p ; hsa-mir-4670-3p ; hsa-mir-6837-3p ; hsa-mir-6754-3p ; hsa-mir-412-3p ; hsa-mir-5692a ; hsa-mir-141-5p ; hsa-mir-335-3p ; hsa-mir-5096 ; hsa-mir-3658 ; hsa-mir-505-3p ; hsa-mir-3653-3p ; hsa-mir-5093 ; hsa-mir-3688-3p ; hsa-mir-580-5p ; hsa-mir-6507-5p ; hsa-mir-23a-3p ; hsa-mir-130a-5p ; hsa-mir-23b-3p ; hsa-mir-23c ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-3679-3p ; hsa-mir-4777-5p ; hsa-mir-526a ; hsa-mir-523-5p ; hsa-mir-522-5p ; hsa-mir-520c-5p ; hsa-mir-519c-5p ; hsa-mir-519b-5p ; hsa-mir-519a-5p ; hsa-mir-518f-5p ; hsa-mir-518e-5p ; hsa-mir-518d-5p ; hsa-mir-6826-3p ; hsa-mir-520g-5p ; hsa-mir-4667-3p ; hsa-mir-6795-3p ; hsa-mir-6887-3p ; hsa-mir-586 ; hsa-mir-2278 ; hsa-mir-5700 ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-19a-5p ; hsa-mir-18a-5p ; hsa-mir-29b-3p ; hsa-let-7a-5p ; hsa-let-7e-5p

Nearest miRNA

hsa-mir-10398/Upstream/2639135; hsa-mir-1202/Downstream/556822;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/10387, chr6-CpG: 65/Downstream/228660

Nearest cancer related gene

TNFAIP3(TSG, No orient, 0)

Downstream sequence

TTTGTGTATTCTCATACATATTTTTTCCTTTTGGTCTTCAGGTTGGATGAA

Junction sequence