Basic Information
VIS ID
TVIS42001125
Fusion event
EBV-chr7:q36.3 integration
Validated
No
Detection method
GenCap Enrichment+NGS
Data source
Curated
Sample type
Tumor
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25355872
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
50100
Orient
+
Integrated sequence
CCTGTCACCACCTCCCTGATAATGTCTTCAATAGACAGAAATTGGGTGACCACTGAGGGAGTGTTCCACAGTAATGTTGTCTGGTCGCTAGATGGCGCGG| |GTGAGGCCACGCTTTGCGAAAACGAAAGTGCTTGAAAAGGCGCGGGATAGCGTGCGCTACCGGATGGCGGGTAATACATGCTATCCTTACATTTTGGCAT
Host Sequence
Chromosome
chr7
Cytoband
q36.3
Reference genome
GRCh37/hg19
Start
158387979/158595287 (Hg38)
End
158387979/158595287 (Hg38)
Orient
+
Location type
Intergenic;Intergenic
Fragile sites / regions
FRA7I
Nearest miRNA
hsa-mir-10399/Upstream/3591;
Nearest TSS
ENST00000635602/Upstream/4658; ENST00000397143/Downstream/69945;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/6758, chr7-CpG: 94/Downstream/109179
Nearby gene
MIR5707(-3354) ;
Upstream sequence
ttttatattttaattccatttttcccacaaactttttgaagtcACTGACATTCAGTAACGAGTGAGATTTACTCTTCTTTAGTAAACTGCATTACTAAAA
Downstream sequence
cgaagttgtaacagaggtggagCTGGTGGTGATGGAAGTGTCAGTGGTGGTGATGCTTCTGTCTGCACATCCCCTTTCCCATTTAGGCAAACAGCACTGC
Reference
Cao, S., et al.High-throughput RNA sequencing-based virome analysis of 50 lymphoma cell lines from the Cancer Cell Line Encyclopedia project. J Virol,2015, 89(1): 713-729.
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