VISDB Viral Integration Site DataBase

VIS ID

TVIS42001134

Fusion event

EBV-ZNF385D integration

Validated

No

Detection method

GenCap Enrichment+NGS

Data source

Curated

Sample type

Disease

Nasopharyngeal carcinoma (NPC)

Quality evaluation

Normal

Reported year

2015

PubMed ID

Virus name

EBV

Reference genome

Start

156840

Orient

+

Integrated sequence

GGTGATGGACTGACCCACGCTACCCAGACTGTCCATAAGTTCCCCCAGGCCGTCCACGAATTGATTTCTTCCGTTTGACACTGCATTGTCCAAATCCTTC| |CGCAGGCCGGCGATGTTTTGCGCCTGGAAGTTGTACTCCCGGAAGATGCCCTCCAGGTCAAAGACGTTGGAGGCACGCTGTTCGTCCCGTGAGTACAGCT

Chromosome

chr3

Cytoband

p24.3

Reference genome

Start

End

22114254/22072762 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-6868-3p ; hsa-mir-627-3p ; hsa-mir-6734-3p ; hsa-mir-3667-3p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-623 ; hsa-mir-2355-5p ; hsa-mir-3124-3p ; hsa-mir-5088-3p

Nearest miRNA

hsa-mir-12127/Upstream/1935121; hsa-let-7g/Downstream/3592111;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/1886298, chr3-CpG: 86/Downstream/299239

Upstream sequence

GTTCTGTTAGGACAGAACACTTTTAAAATCCAAGTTTTGAGATAATATCTAAGATTTGTCCCAAGAGAAACTGCAGATCCCAGAGTCTGACATATATAAA

Downstream sequence

ttgggagaaggaaggaaaaagggaatgcagaagaaataaggaaACAGAACAAAAGGAAAGGTAAGGACTGGATTCTTAGTGTCCTAGAATACATATTCTT