Basic Information
VIS ID
TVIS42001137
Fusion event
EBV-DLEC1 integration
Validated
No
Detection method
GenCap Enrichment+NGS
Data source
Curated
Sample type
Tumor
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25355872
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
128793
Orient
-
Integrated sequence
ATTATTGCCAAAACAACGTGTGCTCTTTCTTCATACAGGCCCGCAATTTCCATGACAGTCCCGTTGGTGGTCAGCAGCAGATAGTGAACGTGGAGGTTGT| |CAAAATCAAAGTAGTTGGAGCTCAAGATGGAGTTTTGGACTTCCTGGGAGGTGATGTAGGTTGTAGTTTCCAGGCCTTCCTTTTCATCATAACTGAGCAG
Host Sequence
Chromosome
chr3
Cytoband
p22.2
Reference genome
GRCh37/hg19
Start
38125978/38084487 (Hg38)
End
38125978/38084487 (Hg38)
Orient
-
Location type
Intronic
Target gene
DLEC1
Nearest miRNA
hsa-mir-12127/Upstream/115007; hsa-let-7g/Downstream/1053719;
Nearest TSS
ENST00000440867/Upstream/21709; ENST00000477260/Downstream/25323;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/44791, chr3-CpG: 54/Downstream/52024
Nearest cancer related gene
DLEC1(TSG, No orient, 0)
Upstream sequence
ACAAAATATGTAGAATATTTTACCCTAGTCTCAGTATCTCTGTACATAGAACTTTGGAATGATTTTAGTTAATGAGGGAAAAAAAAAAAAACATATTGGT
Downstream sequence
ggtggtagtagtagtggtagtagtagtagtggtagtagtagtagtggtggtggtagtagtagtggtagtagtagtggtagtagtagtagtgggggggtgg
Reference
Cao, S., et al.High-throughput RNA sequencing-based virome analysis of 50 lymphoma cell lines from the Cancer Cell Line Encyclopedia project. J Virol,2015, 89(1): 713-729.
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