Basic Information
VIS ID
TVIS43000037
Fusion event
MCV-chr5:q11.2 integration
Validated
Yes
Detection method
RACE
Data source
Curated
Sample type
Cell line
Disease
Merkel cell carcinoma (MCC)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23085629
Virus Sequence
Virus name
MCV
Reference genome
EU375803
Start
2843
Integrated sequence
AAGATTTAGTTATACTTTACACTTTTTCCCAAAGGCAAATCTAAGAGATTCCCTGGATCAGAACATGGAAATAAGAAAAAGAAGAATTCTTCAAAGTGGA| |ACCACTTTATTGCTTTGTCTTATTTGGTGCTTGCCTGATACAACCTTTAAGCCTTGCTTACAAGAAGAAATTAAAAACTGGAAGCAAATTTTACAGAGTG
Host Sequence
Chromosome
chr5
Cytoband
q11.2
Reference genome
GRCh37.p5
Start
2282589/2282475 (Hg38)
End
2282589/2282475 (Hg38)
Location type
Non-coding region
Nearest miRNA
hsa-mir-4277/Upstream/573607; hsa-mir-10397/Downstream/4545378;
Nearest TSS
ENST00000502646/Upstream/314381; ENST00000626215/Downstream/430116;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/102122, chr5-CpG: 27/Downstream/281908
Upstream sequence
GCAGGGACACGCAAGGGTGCTTGTGGCTTGGCTGCTCTTCCTGGAAGGAGGCAGAGGTGGGCTCAGCGAGGTCAAAGGTCAGCAGGGCCATTGTGGGGCT
Downstream sequence
CAGGGCCTGATGGACAGGTAGCAGGTGAGCATCAGGTGGGCCTGTGACAGGCAGGTGAGGAATAGGTAGCACTGCAGGCAGGCGAAGGGCAGGTGGGCCT
Target sequence
TGGCCTCTGACTGGGTCATCGTGTCCAGTGATGGCCAAGGACAGATAGAGGCAGAGCGGGCCTGACCCAGGCCCTCCTTGGGCAACGTGGAGGAGCAGG
Reference
Guastafierro, A., et al. Characterization of an early passage Merkel cell polyomavirus-positive Merkel cell carcinoma cell line, MS-1, and its growth in NOD scid gamma mice. J Virol Methods,2013,187(1): 6-14.
Curate