Basic Information
VIS ID
TVIS43000048
Fusion event
MCV-LINC01994 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Tumor
Disease
Merkel cell carcinoma (MCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28049147
Virus Sequence
Virus name
MCV
Reference genome
HM355825.1
Host Sequence
Chromosome
chr3
Cytoband
q26.33
Reference genome
GRCh37/hg19
Start
182180601/182462813 (Hg38)
End
182180601/182462813 (Hg38)
Location type
Intronic
Target gene
LINC01994
Nearest miRNA
hsa-let-7g/Upstream/5947662; hsa-mir-1224/Downstream/1423987;
Nearest TSS
ENST00000440867/Upstream/97666; ENST00000492416/Downstream/23551;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/735601, chr3-CpG: 70/Downstream/219477
Upstream sequence
AAATAAGCATTTAAGATCTAATTATAATTAGATTGATGTGACTGGCAGTGAACCTGAAAGAGCACTGGATAAGGATCTTTTTGTATGTCACCAAgtcaag
Downstream sequence
tctttgttgaagatctttgtttgttcttgcattgctgtcttgatctctgtgagcatctttatgatcattattttgaatttcctgtcaggtaaatcacaaa
Reference
Starrett, G. J., et al. Merkel Cell Polyomavirus Exhibits Dominant Control of the Tumor Genome and Transcriptome in Virus-Associated Merkel Cell Carcinoma. MBio,2017, 8(1).
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