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TVIS43000049
Basic Information
VIS ID
TVIS43000049
Fusion event
MCV-ECH1 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Tumor
Disease
Merkel cell carcinoma (MCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28049147
Virus Sequence
Virus name
MCV
Reference genome
HM355825.1
Host Sequence
Chromosome
chr19
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
39307703/38817063 (Hg38)
End
39307703/38817063 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
ECH1
miRNAs that regulate target gene
hsa-mir-193b-3p
;
hsa-mir-340-5p
;
hsa-mir-26b-5p
;
hsa-mir-378a-3p
;
hsa-mir-320a
;
hsa-mir-186-5p
;
hsa-mir-23b-3p
Nearest miRNA
hsa-mir-10395/Upstream/3471436; hsa-let-7e/Downstream/592560;
Nearest TSS
ENST00000633603/Upstream/793;
ENST00000594558/Downstream/301;
Nearest CpG islands
None/Target,
chr19-CpG: 112/Upstream/24041
,
chr19-CpG: 35/Downstream/14561
Upstream sequence
tggtttccggagctggttgctgcacaggttttgggccacagttttgttgccatgtatggattggccattgtccTGCACCTCTTCTGCCTCTTACCAGGAG
Downstream sequence
CCTTCACCTGGAAGAAAGCATCCTGGGCACAGTACCGGATGTCACAGGCGGTGACAAGGTCCACACCTAGGAGGTAGAGGCCAGGGATGCTGAATGACCA
Reference
Starrett, G. J., et al. Merkel Cell Polyomavirus Exhibits Dominant Control of the Tumor Genome and Transcriptome in Virus-Associated Merkel Cell Carcinoma. MBio,2017, 8(1).
Sample Information
×
Sample name
Tumor-146
Sample type
Tumor
Age
77
Gender
Male
CpG Island Information
×
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