Basic Information
VIS ID
TVIS44000002
Fusion event
HTLV-1-OVGP1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
111964019/111421397 (Hg38)
End
111964019/111421397 (Hg38)
Orient
+
Location type
Exonic
Target gene
OVGP1
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-101-1/Upstream/1822430; hsa-mir-11399/Downstream/1040373;
Nearest TSS
ENST00000473358/Upstream/4718; ENST00000493119/Downstream/1654;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/74480, chr1-CpG: 68/Downstream/27285
Upstream sequence
TCTTGCTTGGTGTACTTCCCTGGAGATGCTGGTCCGATCGCTCTGGCCTGCAACCCATTCTTAGAGGCTTTGAGGAGGCGAAAGGTACGTCCATAGGTGG
Downstream sequence
GGATCCCCATGATGAGCTTCTCTGAGGGTGCCCCAAGCTTTCTCCAATAATTCATAGCATATGCCTGCAGGTAAGAAGAATCCAGACTCCTCCTTGTTAC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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