VISDB Viral Integration Site DataBase

VIS ID

TVIS44000034

Fusion event

HTLV-1-TFAM integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr10

Cytoband

q21.1

Reference genome

Start

End

60152975/58393215 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-15a-3p ; hsa-mir-484 ; hsa-mir-34a-5p ; hsa-mir-92a-3p ; hsa-mir-26a-5p ; hsa-mir-200a-3p ; hsa-mir-494-3p ; hsa-mir-448 ; hsa-mir-203b-3p ; hsa-mir-337-3p ; hsa-mir-4424 ; hsa-mir-4679 ; hsa-mir-4677-3p ; hsa-mir-5590-3p ; hsa-mir-142-5p ; hsa-mir-101-5p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-3912-3p ; hsa-mir-4796-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-3609 ; hsa-mir-548ah-5p ; hsa-mir-2054 ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-6878-5p ; hsa-mir-613 ; hsa-mir-206 ; hsa-mir-1-3p ; hsa-mir-6128 ; hsa-mir-4254 ; hsa-mir-3690 ; hsa-mir-6871-5p ; hsa-mir-499a-5p ; hsa-mir-4719 ; hsa-mir-8087 ; hsa-mir-4432 ; hsa-mir-6083 ; hsa-mir-8485 ; hsa-mir-8064 ; hsa-mir-6767-3p ; hsa-mir-199a-3p ; hsa-mir-155-5p ; hsa-mir-1178-5p ; hsa-mir-1182 ; hsa-mir-4662a-3p

Nearest miRNA

hsa-mir-1265/Upstream/1088656; hsa-mir-107/Downstream/4979742;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/7640, chr10-CpG: 121/Downstream/119525

Upstream sequence

accacaggcacgtgccaccacacctggctaattttttatatttttagtagagatggggtttcaccatattggccaggctggtctcgaactcctgacctca

Downstream sequence

tgatctgcctgcctcggcctcccaaagtactgggattacaggcgtgagccaccacacctggccctaatctctttttaaacagtctttcagccaatcttgt