Basic Information
VIS ID
TVIS44000042
Fusion event
HTLV-1-TDRP integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
p23.3
Reference genome
GRCh37/hg19
Start
445227/495227 (Hg38)
End
445227/495227 (Hg38)
Orient
+
Location type
Intronic
Target gene
TDRP
miRNAs that regulate target gene
hsa-mir-221-3p ; hsa-mir-24-3p ; hsa-mir-3671 ; hsa-mir-1295b-3p
Nearest miRNA
hsa-mir-10400/Downstream/1305898;
Nearest TSS
ENST00000518652/Upstream/217; ENST00000631653/Downstream/49618;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/87553, chr8-CpG: 189/Downstream/48928
Upstream sequence
gaagctgaggtgggaggatcacttgagacccaggaggtcaaggctgcagagaactgtgatctcaccactgcactccaggctgggcaacagagcaagaccc
Downstream sequence
catctcaaaaaacaaaCAACAGCAACAACAACAAAACACATAGGAGACTGACCTTTGAGAAGGTTGTTACAAGAGGTCCCCTAGAAGGGGGTCTTCTCCA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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