Basic Information
VIS ID
TVIS44000050
Fusion event
HTLV-1-chr11 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
69906648/70060542 (Hg38)
End
69906648/70060542 (Hg38)
Orient
-
Location type
ncRNA_intronic
Fragile sites / regions
FRA11H ; FRA11A
Nearest miRNA
hsa-mir-10392/Upstream/977284; hsa-let-7a-2/Downstream/223413;
Nearest TSS
ENST00000527297/Upstream/39483; ENST00000531604/Downstream/3382;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/74164, chr11-CpG: 116/Downstream/17690
Nearby gene
LOC105369371(+2610) ;
Upstream sequence
gctatatgtattagggaaacacagtcgtgtggttcaggacttgtgttgggtgctaagtgagaaactgggctgaaattgggcccatggtaatagctactgt
Downstream sequence
tggagtttcaacaaatagtgaatagagctggaggagtcgagaggcagacaataaatgtgaaaggtgtgaggaggatattaatgcttgaaggttgtgagaa
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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