Basic Information
VIS ID
TVIS44000051
Fusion event
HTLV-1-CEP83 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q22
Reference genome
GRCh37/hg19
Start
94704603/94310827 (Hg38)
End
94704603/94310827 (Hg38)
Orient
-
Location type
Intronic
Target gene
CEP83
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-124-3p ; hsa-mir-26b-5p
Nearest miRNA
hsa-let-7i/Upstream/7565678; hsa-mir-1178/Downstream/250962;
Nearest TSS
ENST00000382841/Upstream/27983; ENST00000623122/Downstream/2351;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/123729, chr12-CpG: 79/Downstream/148733
Upstream sequence
CtggattgaagcttacaaaattgccatttttaaataggtgaaatatggtcaaatatagagattttcatagttcaatctaaTTTTCAAAATGTCAGtgtaa
Downstream sequence
tattttagtaagaaatatatatttggtctttgcccttggttcctggcacacagctcctaaaactctgggaaactctgaagtgataagagtatcttttgta
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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