Basic Information
VIS ID
TVIS44000061
Fusion event
HTLV-1-chr16 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
84675932/84642326 (Hg38)
End
84675932/84642326 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1225/Upstream/1133918; hsa-mir-11401/Downstream/565470;
Nearest TSS
ENST00000527434/Upstream/24249; ENST00000565743/Downstream/6199;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/24079, chr16-CpG: 127/Downstream/5828
Nearby gene
KLHL36(+6185) ;
Upstream sequence
GAGAGATTTGACGGGTCCAAAGGAAACGAGGCTCACACAGGGTTACCTGCTGAGCCTGGGGTCCAGCCAGGTTTGCAACCTTGAAATCCTAAGTCCCTGA
Downstream sequence
GCCACTTCATTTCTATAGTTGTCAGAGAGACATGCAATCAGGTCCAGCGTGCCTTGGAGGAACAGGTTGTGGGCAATGCCAGCCTGGCTGGGGACCTCAG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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