Basic Information
VIS ID
TVIS44000064
Fusion event
HTLV-1-FBF1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
73923747/75927666 (Hg38)
End
73923747/75927666 (Hg38)
Orient
-
Location type
Intronic
Target gene
FBF1
Nearest miRNA
hsa-mir-10226/Upstream/143059; hsa-mir-1250/Downstream/170353;
Nearest TSS
ENST00000595228/Upstream/4193; ENST00000587348/Downstream/2463;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/9371, chr17-CpG: 58/Downstream/13134
Upstream sequence
GTCTCTCCTGGCCAAAGTCCTCCTCCCATATCATGGACTGGGGCCCCTGGGATGGGGTGCACTTCTTCCTGGGAAGCTGGGGGCTCATGGCCATGGGCAC
Downstream sequence
AGCCAAGGGAGGAGTCTCCAGTTCTGCCATGGGCTTCTGGCAGGGAAACGAGGTAGGAGCTACCTCTGCTTCCTCATCATGAGTCACTCCAGAGACATGG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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