Basic Information
VIS ID
TVIS44000066
Fusion event
HTLV-1-chr18 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
31925332/34345368 (Hg38)
End
31925332/34345368 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA18A
Nearest miRNA
hsa-mir-1-2/Upstream/4046408; hsa-mir-122/Downstream/1246369;
Nearest TSS
ENST00000575820/Upstream/119438; ENST00000588771/Downstream/147922;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/120457, chr18-CpG: 116/Downstream/148112
Nearby gene
NOL4(-121817) ;
Upstream sequence
TTATTCCATAGATTTTACATATTGCCAGTGCCAGCAACATATAGGTAGTGGATGATTTCTGCCCACACTTTGTGAGCAGCCTCCTCATAAATCCCAAAAG
Downstream sequence
TTAATAATGACAAAAAGCAGTCTTGTCTATTCCCTTTAAAAGCCTGAAGCAATTTGTTCAGCAACCACACTGCTAAGGTAGAGATAAAGAAAAGGAGCAT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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