Basic Information
VIS ID
TVIS44000081
Fusion event
HTLV-1-DNAJC18 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q31.2
Reference genome
GRCh37/hg19
Start
138767557/139431868 (Hg38)
End
138767557/139431868 (Hg38)
Orient
-
Location type
Intronic
Target gene
DNAJC18
miRNAs that regulate target gene
hsa-mir-122-5p ; hsa-mir-4701-5p ; hsa-mir-4715-3p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-1227-3p ; hsa-mir-365b-5p ; hsa-mir-365a-5p ; hsa-mir-8052 ; hsa-mir-3199 ; hsa-mir-6778-3p ; hsa-mir-4740-3p ; hsa-mir-455-5p ; hsa-mir-4438
Nearest miRNA
hsa-mir-10397/Upstream/1784219; hsa-mir-103a-1/Downstream/1131803;
Nearest TSS
ENST00000502646/Upstream/5639; ENST00000637503/Downstream/5692;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/27645, chr5-CpG: 48/Downstream/86007
Upstream sequence
attgccatattgttttccaaactggctgcattcctaccagcaatgtacaaaggttccaatttatctgcttctttataaacacttatcatccacctttttg
Downstream sequence
actatagacattccagtgggtatatctcattgtggttttgatttgcatttccctaatgactaaagatgttgaacaagtttacatatgcttactaaccata
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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