Basic Information
VIS ID
TVIS44000102
Fusion event
HTLV-1-chr11 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p14.3
Reference genome
GRCh37/hg19
Start
25226475/25204929 (Hg38)
End
25226475/25204929 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-210/Upstream/1785739; hsa-let-7a-2/Downstream/2310041;
Nearest TSS
ENST00000527297/Upstream/313164; ENST00000533942/Downstream/529841;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/707737, chr11-CpG: 29/Downstream/1127061
Nearby gene
LUZP2(+122289) ;
Upstream sequence
ttttccacagataccaagtaagtgaggcccaaactcagttattctgattttcCAAGGATACATGGGTACTCTCAAAATTACTTCTTGTCAGTCAATTCTA
Downstream sequence
AAATTGCTAGTTACAGAATGAGGTACTTCAGGTAATCAACATTTAGTGTCCGAAATATTTCATCTGCTCTTATCATTTGTCTGTGTTTTCTGGATGATTG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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