VISDB Viral Integration Site DataBase

VIS ID

TVIS44000109

Fusion event

HTLV-1-ARL6IP1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr16

Cytoband

p12.3

Reference genome

Start

End

18810336/18799014 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-130b-3p ; hsa-mir-133a-3p ; hsa-mir-27a-3p ; hsa-mir-19b-3p ; hsa-mir-1229-3p ; hsa-mir-877-3p ; hsa-mir-423-5p ; hsa-let-7f-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-mir-570-3p ; hsa-mir-129-5p ; hsa-mir-138-1-3p ; hsa-mir-5580-3p ; hsa-mir-4328 ; hsa-mir-218-5p ; hsa-mir-27b-3p ; hsa-mir-513a-5p ; hsa-mir-593-5p ; hsa-mir-222-3p ; hsa-mir-221-3p ; hsa-mir-548v ; hsa-mir-187-5p ; hsa-mir-4784 ; hsa-mir-3150b-3p ; hsa-mir-1208 ; hsa-mir-195-3p ; hsa-mir-16-2-3p ; hsa-mir-3146 ; hsa-mir-4703-5p ; hsa-mir-3942-5p ; hsa-mir-583 ; hsa-mir-1276 ; hsa-mir-4311 ; hsa-mir-3120-3p ; hsa-mir-633 ; hsa-mir-135a-3p ; hsa-mir-7845-5p ; hsa-mir-551b-5p ; hsa-mir-3143 ; hsa-mir-488-5p ; hsa-mir-5586-5p ; hsa-mir-543 ; hsa-mir-5692a ; hsa-mir-3658 ; hsa-mir-3653-3p ; hsa-mir-642b-5p ; hsa-mir-219a-2-3p ; hsa-mir-1247-5p ; hsa-mir-34a-3p ; hsa-mir-6507-5p ; hsa-mir-6851-3p ; hsa-mir-6775-3p ; hsa-mir-1291 ; hsa-mir-153-5p ; hsa-mir-4704-3p ; hsa-mir-23a-3p ; hsa-mir-130a-5p ; hsa-mir-23b-3p ; hsa-mir-23c ; hsa-mir-328-3p ; hsa-mir-335-3p ; hsa-mir-30e-3p ; hsa-mir-30d-3p ; hsa-mir-30a-3p ; hsa-mir-3127-5p ; hsa-mir-539-5p ; hsa-mir-1251-5p ; hsa-mir-517-5p ; hsa-mir-6754-5p ; hsa-mir-4441 ; hsa-mir-4270 ; hsa-mir-211-3p ; hsa-mir-3675-3p ; hsa-mir-216b-5p ; hsa-mir-10a-3p ; hsa-mir-130a-3p ; hsa-mir-1323 ; hsa-mir-148a-3p ; hsa-mir-148b-3p ; hsa-mir-152-3p ; hsa-mir-301a-3p ; hsa-mir-301b-3p ; hsa-mir-3126-5p ; hsa-mir-3129-3p ; hsa-mir-3529-3p ; hsa-mir-3666 ; hsa-mir-4295 ; hsa-mir-4419a ; hsa-mir-4436b-3p ; hsa-mir-4482-3p ; hsa-mir-4510 ; hsa-mir-454-3p ; hsa-mir-4632-5p ; hsa-mir-4719 ; hsa-mir-5094 ; hsa-mir-513b-5p ; hsa-mir-548o-3p ; hsa-mir-5583-5p ; hsa-mir-5586-3p ; hsa-mir-6127 ; hsa-mir-6129 ; hsa-mir-6130 ; hsa-mir-6133 ; hsa-mir-6504-3p ; hsa-mir-656-3p ; hsa-mir-6735-5p ; hsa-mir-6760-5p ; hsa-mir-6834-5p ; hsa-mir-6875-5p ; hsa-mir-6878-5p ; hsa-mir-6879-5p ; hsa-mir-7159-3p ; hsa-mir-759 ; hsa-mir-7843-5p ; hsa-mir-95-5p

Nearest miRNA

hsa-mir-1225/Upstream/304438; hsa-mir-11401/Downstream/2707035;

Nearest TSS

Nearest CpG islands

None/Target, chr16-CpG: 29/Upstream/8470, chr16-CpG: 92/Downstream/2051

Upstream sequence

CTCCAAATACAAAAAATAACCTCTTAACCAAATTGCCAATTTTAAACTAGTTGGTTTCTGAAAAACTGCAATTTCAAAGATGAAAATACAATGGGttttt

Downstream sequence

ttgttttttgtgtttttttttttgagacggagtctcgctctgtcacccaggctggagtgcagtggggagatctcggctcactgcagcctccgcctcctgg