Basic Information
VIS ID
TVIS44000111
Fusion event
HTLV-1-ASIC2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
31588790/33261772 (Hg38)
End
31588790/33261772 (Hg38)
Orient
+
Location type
Intronic
Target gene
ASIC2
Nearest miRNA
hsa-mir-1180/Upstream/911570; hsa-mir-10226/Downstream/3771973;
Nearest TSS
ENST00000595228/Upstream/149914; ENST00000585093/Downstream/29335;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/333267, chr17-CpG: 216/Downstream/29555
Upstream sequence
ggcaaatactatgattatatgagccacacaacagaggaggaaactgaggcacagataagtgacttgcaagcagtcagctgggatttgaactcagaaagtc
Downstream sequence
tgctccagaatccatgctttcaaccCTGGAATCCTAGTCACGACGAGGTGAACGTGGGGGGTGCTGGCTGCCTTCACTCCAGAGGCGTCTCCTATCCCAG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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