Basic Information
VIS ID
TVIS44000112
Fusion event
HTLV-1-chr17 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p12
Reference genome
GRCh37/hg19
Start
12289016/12385699 (Hg38)
End
12289016/12385699 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA17A
Nearest miRNA
hsa-mir-1253/Upstream/303703; hsa-mir-10226/Downstream/531569;
Nearest TSS
ENST00000595228/Upstream/184099; ENST00000577679/Downstream/164083;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/364145, chr17-CpG: 70/Downstream/279651
Nearby gene
LINC00670(No orient, 164269)
Upstream sequence
CTTCCCTCTCCTATATATATGGCAGGTAACATTTGTTTGGCTCTTTTAACTCCAATTAAAGCATTTTtgtgtgtgtgtgcttgtgtgtgtgtgtgCATAT
Downstream sequence
ACATTTATTCTTTTTTCCTCAGAGGCACACACACATATTTATGCACTTGGAGACAATGAAAACTATTATTTTCCAGATGCCAGAAAAGAGTTGCTTTGAC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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