Basic Information
VIS ID
TVIS44000126
Fusion event
HTLV-1-LOC105377110 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p14.2
Reference genome
GRCh37/hg19
Start
59132111/59146385 (Hg38)
End
59132111/59146385 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA3B
Target gene
LOC105377110
Nearest miRNA
hsa-let-7g/Upstream/3293791; hsa-mir-12124/Downstream/1471420;
Nearest TSS
ENST00000440867/Upstream/81235; ENST00000475527/Downstream/242319;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/96167, chr3-CpG: 48/Downstream/2104547
Nearby gene
C3orf67(No orient, 96396)
Upstream sequence
AATACACATAATatccacatgagtgtaaggtggtatctcattgtggtttcgatttgcatttccctaatgattagtgatgctaaacatctattcatgtgtt
Downstream sequence
taatgccattcatgtatcttctttggagaaatgtctatccaaattctctgcccatttttaaattgagtcatttgattttgttgttgttgagttcggagtt
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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