Basic Information
VIS ID
TVIS44000168
Fusion event
HTLV-1-chr22 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q13.32
Reference genome
GRCh37/hg19
Start
48517386/48121569 (Hg38)
End
48517386/48121569 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA22A
Nearest miRNA
hsa-let-7a-3/Upstream/2007801; hsa-mir-12114/Downstream/152795;
Nearest TSS
ENST00000624155/Upstream/68923; ENST00000446364/Downstream/19432;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/907997, chr22-CpG: 25/Downstream/87776
Nearby gene
MIR3201(+152790) ;
Upstream sequence
ggctgcacctgaatggttctctgttttatcccaggctctagaacaaagcctggcaaacagaagacactctgttttgtggaatgaatgaatGTATAAATGA
Downstream sequence
ATGAGTGGATGGATGACTTCCATAATATTTATAATCTATAATATCTCTCTTCTGCCATTTATTTTTTAACTGCCATGAATTCCAGATATTTCTAGGCATG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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