Basic Information
VIS ID
TVIS44000175
Fusion event
HTLV-1-IFT43 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
76463702/75997359 (Hg38)
End
76463702/75997359 (Hg38)
Orient
+
Location type
Intronic
Target gene
IFT43
Nearest miRNA
hsa-mir-208a/Upstream/1517155; hsa-mir-1185-1/Downstream/1268859;
Nearest TSS
ENST00000550708/Upstream/11565; ENST00000554423/Downstream/24966;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/11160, chr14-CpG: 22/Downstream/133946
Upstream sequence
GTATTTGAAACCAGCCCCTTTGGCCTTCCTTGATAAATGGACCAAGTGTTTGAAAACCAGCCCCTTTGCCTTTTCACAAATGACCTATATGAGGTCAACA
Downstream sequence
TTTCTAATATGACACTGAAATAATTGGTAATGTTATGAGAACTAAACAGTGAGCTTTCAGTATTTTTAGCCTTGTCTTTTATTGCTGCATCTTCAGTGCA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Curate