Basic Information
VIS ID
TVIS44000186
Fusion event
HTLV-1-DPP10 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
115800245/115042668 (Hg38)
End
115800245/115042668 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
DPP10
Nearest miRNA
hsa-mir-1285-2/Upstream/1321300; hsa-mir-10b/Downstream/12380869;
Nearest TSS
ENST00000437798/Upstream/207080; ENST00000492708/Downstream/21905;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/379984, chr2-CpG: 185/Downstream/118492
Upstream sequence
TATTTTGAACACATTTTACTCTTGGCTATTGATGCACGGAGTGTTAGAGCTGAAATAGTTCTTAATTTTGGTCTCTCCTACTGTAGATCAGGAAGGCAAG
Downstream sequence
AGATAGAGAGGACAAATGAGCTATTCAAAGAGCAGAGGGTCACAAATAGAACTAGCGTTCTCCTCAAGCCATCTTGATCCATCAGTTTCAATTCATGCTA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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