Basic Information
VIS ID
TVIS44000202
Fusion event
HTLV-1-chr8 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
90835606/89823378 (Hg38)
End
90835606/89823378 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-12123/Upstream/9581905; hsa-mir-10400/Downstream/1382107;
Nearest TSS
ENST00000518652/Upstream/43290; ENST00000520659/Downstream/78481;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/65149, chr8-CpG: 137/Downstream/78591
Nearby gene
RIPK2(+32314) ;
Upstream sequence
GCATTTGCCATAGTGCACACAGCAGAAAAGTGGACGAAGCTGAACTCTACCTCAGGAGGGGAGTAGACTATTTCTTTAAGACAACTGCAAATCTCTCCTC
Downstream sequence
TAATCCTTCATGTCATGACTTTTTCCCCACTCTTCCAGTAAGCTTTTATTATCACTTAAGTCATGATTCAGGGTCCCACGATGAGCTCCATGTACCCAAG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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