Basic Information
VIS ID
TVIS44000236
Fusion event
HTLV-1-LARGE1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q12.3
Reference genome
End
33559570/33163584 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-1286/Upstream/1542053; hsa-let-7a-3/Downstream/272998;
Nearby gene
SYN3(-105193) ;
Upstream sequence
TACAGGTACATTCACTTAACAGGCTCTCTTTCCACCCTTGTAGAAATACAAAAATAAGACTTAATACAGACGATGGCATGGGCTTAGTAACTACCCCTTT
Downstream sequence
ACCCTTAAACAGCTCATTGCCCCTTTACAGGGAAGGGCTAAGTACAGTGTACGGTTTTATCACATTCCAGTGTAAGAAATGCATCGTGAAAAGCAGATGG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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