VISDB Viral Integration Site DataBase

VIS ID

TVIS44000277

Fusion event

HTLV-1-RFC2 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr7

Cytoband

q11.23

Reference genome

Start

End

73648845/74234515 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-1-3p ; hsa-mir-149-5p ; hsa-mir-196a-5p ; hsa-mir-3152-5p ; hsa-mir-6836-3p ; hsa-mir-106a-3p ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-593-5p ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-767-5p ; hsa-mir-4999-3p ; hsa-mir-183-5p ; hsa-mir-454-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-301b-3p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-130a-3p ; hsa-mir-5197-5p ; hsa-mir-665 ; hsa-mir-1273g-5p ; hsa-mir-1304-5p ; hsa-mir-6765-5p ; hsa-mir-6807-5p ; hsa-mir-4266 ; hsa-mir-6894-5p ; hsa-mir-7160-5p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-202-3p ; hsa-mir-98-5p ; hsa-mir-4500 ; hsa-mir-4458 ; hsa-let-7i-5p ; hsa-let-7g-5p ; hsa-let-7f-5p ; hsa-let-7e-5p ; hsa-let-7d-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-3188 ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-2467-5p ; hsa-mir-3975 ; hsa-mir-1233-3p ; hsa-mir-1225-3p ; hsa-mir-7162-3p ; hsa-mir-3664-3p ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-6500-3p ; hsa-mir-3614-5p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-4779 ; hsa-mir-4695-5p ; hsa-mir-510-5p ; hsa-mir-512-5p ; hsa-mir-1200 ; hsa-mir-1976 ; hsa-mir-23a-5p ; hsa-mir-23b-5p ; hsa-mir-3653-5p ; hsa-mir-4279 ; hsa-mir-4324 ; hsa-mir-4722-3p ; hsa-mir-498 ; hsa-mir-544b ; hsa-mir-5571-5p ; hsa-mir-619-5p ; hsa-mir-6506-5p ; hsa-mir-660-3p ; hsa-mir-6727-3p ; hsa-mir-6747-3p ; hsa-mir-6791-3p ; hsa-mir-6829-3p ; hsa-mir-6869-5p

Nearest miRNA

hsa-mir-1183/Upstream/43221; hsa-mir-10399/Downstream/361453;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/59504, chr7-CpG: 82/Downstream/19548

Upstream sequence

ggctgaattttactctatgtaaattaaacctcaattaatctaaccttgaaaaaTCAATCAATCAGTCAATACACAAGAGAGCCTTGAATGAAGAAAATCA

Downstream sequence

GAACTGTGTGAAACAAACTTGGTCCTCAGGACAATCAGCCACGTTGATCtagtttggacgtctgtccccttccaatctcatttggaatttggtccccaat