Basic Information
VIS ID
TVIS44000303
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
129783774/129026201 (Hg38)
End
129783774/129026201 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA2S
Nearest miRNA
hsa-mir-1285-2/Upstream/1602583; hsa-mir-10b/Downstream/2464959;
Nearest TSS
ENST00000437798/Upstream/444625; ENST00000450840/Downstream/45524;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/123828, chr2-CpG: 37/Downstream/561269
Nearby gene
LOC101927881(No orient, 157473)
Upstream sequence
TTTAGAAATGAAAATTATAGTGGAAGTCTGTTTCCACAGACCATAGACCCATGTCCAAGTCTGTTTCGGAGACCACAGACCCATGACCAAGTCTGTTTCC
Downstream sequence
ATAGACCATAGACCCATGTCCAAGTCTGTTTCCACAGACCATAGACCCATGTCCAAGTCTGTTTCCACAGACCATAGACTCATGTCCAAGTCTGTTTCAG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Curate