VISDB Viral Integration Site DataBase

VIS ID

TVIS44000305

Fusion event

HTLV-1-RHOA integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr3

Cytoband

p21.31

Reference genome

Start

End

49417564/49380131 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-31-5p ; hsa-mir-122-5p ; hsa-mir-155-5p ; hsa-mir-185-5p ; hsa-mir-31-3p ; hsa-mir-200c-3p ; hsa-mir-375 ; hsa-mir-124-3p ; hsa-mir-320c ; hsa-mir-146b-5p ; hsa-mir-221-3p ; hsa-mir-133b ; hsa-mir-3613-3p ; hsa-mir-4446-3p ; hsa-mir-1304-3p ; hsa-mir-125a-3p ; hsa-mir-340-5p ; hsa-mir-218-5p ; hsa-mir-4722-5p ; hsa-mir-592 ; hsa-mir-3678-3p ; hsa-mir-597-5p ; hsa-mir-6778-5p ; hsa-mir-1233-5p ; hsa-mir-4741 ; hsa-mir-4675 ; hsa-mir-4687-3p ; hsa-mir-504-3p ; hsa-mir-6499-3p ; hsa-mir-2467-3p ; hsa-mir-4721 ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-6847-5p ; hsa-mir-4779 ; hsa-mir-4519 ; hsa-mir-2278 ; hsa-mir-6509-5p ; hsa-mir-2054 ; hsa-mir-331-5p ; hsa-mir-577 ; hsa-mir-4753-5p ; hsa-mir-1252-3p ; hsa-mir-3646 ; hsa-mir-6768-3p ; hsa-mir-1227-5p ; hsa-mir-3187-3p ; hsa-mir-6881-5p ; hsa-mir-128-2-5p ; hsa-mir-128-1-5p ; hsa-mir-6845-5p ; hsa-mir-6877-5p ; hsa-mir-6762-5p ; hsa-mir-4529-5p ; hsa-mir-5583-3p ; hsa-mir-4517 ; hsa-mir-3936 ; hsa-mir-607 ; hsa-mir-7110-3p ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-483-3p ; hsa-mir-6800-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-200b-3p ; hsa-mir-146a-5p ; hsa-mir-490-3p ; hsa-mir-101-3p ; hsa-mir-133a-5p ; hsa-mir-200b-5p ; hsa-mir-483-5p ; hsa-mir-4456 ; hsa-mir-4520-2-3p ; hsa-mir-4520-3p ; hsa-mir-4640-5p ; hsa-mir-4725-5p ; hsa-mir-4726-5p ; hsa-mir-504-5p ; hsa-mir-541-3p ; hsa-mir-6508-3p ; hsa-mir-654-5p ; hsa-mir-6733-3p ; hsa-mir-6769a-5p ; hsa-mir-6769b-5p ; hsa-mir-6816-3p ; hsa-mir-92a-2-5p

Nearest miRNA

hsa-mir-12127/Upstream/105945; hsa-let-7g/Downstream/426006;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/21622, chr3-CpG: 120/Downstream/31297

Nearest cancer related gene

RHOA(TSG, No orient, 0)

Upstream sequence

agactacacttcctagcttcccttggagacatggccatgtaccatgagatgtgagaatcagcagtatgttgtgggacttccagaaagtctttcttaaagg

Downstream sequence

gaagtctttattatcctcctcctttcctgctgcttaaatctaaagtaagggctggtttctaagcagccatcctggtatgtgagaatgaatgccataccgt