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TVIS44000309
Basic Information
VIS ID
TVIS44000309
Fusion event
HTLV-1-FBXL7 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
p15.1
Reference genome
GRCh37/hg19
Start
15838707/15838598 (Hg38)
End
15838707/15838598 (Hg38)
Orient
+
Location type
Intronic
Target gene
FBXL7
miRNAs that regulate target gene
hsa-mir-3912-5p
;
hsa-mir-527
;
hsa-mir-518a-5p
;
hsa-mir-5681b
;
hsa-mir-31-3p
;
hsa-mir-571
;
hsa-mir-219a-1-3p
;
hsa-mir-520h
;
hsa-mir-520g-3p
;
hsa-mir-4461
;
hsa-mir-5579-5p
;
hsa-mir-520e
;
hsa-mir-520d-3p
;
hsa-mir-520c-3p
;
hsa-mir-520b
;
hsa-mir-520a-3p
;
hsa-mir-373-3p
;
hsa-mir-372-3p
;
hsa-mir-302e
;
hsa-mir-302d-3p
;
hsa-mir-302c-3p
;
hsa-mir-302b-3p
;
hsa-mir-302a-3p
;
hsa-mir-93-5p
;
hsa-mir-526b-3p
;
hsa-mir-519d-3p
;
hsa-mir-20b-5p
;
hsa-mir-20a-5p
;
hsa-mir-17-5p
;
hsa-mir-106b-5p
;
hsa-mir-106a-5p
Nearest miRNA
hsa-mir-10397/Upstream/1012586; hsa-mir-103a-1/Downstream/96584;
Nearest TSS
ENST00000502646/Upstream/231250;
ENST00000329673/Downstream/89290;
Nearest CpG islands
None/Target,
chr5-CpG: 87/Upstream/337784
,
chr5-CpG: 34/Downstream/89381
Upstream sequence
aatttttgtggtaacacaacattcagtctatagcaCCACATTAGGGATTTAGATAAGCACACCCTAGACGGATATTGAGCATCCTCGTTGCTGAATGTAA
Downstream sequence
AAGATCTGCAAGGATTTGTTTCTTTATATCAATGCATATTTCAGCTGTATTTGGCACTGATGACCCTACCTCCTCCTTCTTTTACCCTTGATTTCTTGGT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Sample Information
×
Sample name
ATL7-CR1
Sample type
Nontumor
Age
59
Gender
Female
CpG Island Information
×
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