Basic Information
VIS ID
TVIS44000310
Fusion event
HTLV-1-PHAX integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q23.2
Reference genome
End
125942677/126606985 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-769-3p ; hsa-mir-301a-3p ; hsa-mir-222-3p ; hsa-mir-216a-5p ; hsa-mir-224-3p ; hsa-mir-299-5p ; hsa-mir-522-3p ; hsa-mir-545-5p ; hsa-mir-4797-3p ; hsa-mir-4433a-5p ; hsa-mir-6834-3p ; hsa-mir-4433b-5p ; hsa-mir-566 ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6780a-5p ; hsa-mir-3689c ; hsa-mir-6779-5p ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-6514-3p ; hsa-mir-7977 ; hsa-mir-6799-5p ; hsa-mir-6785-5p ; hsa-mir-6883-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-6811-3p ; hsa-mir-6847-3p ; hsa-mir-214-5p ; hsa-mir-2467-3p ; hsa-mir-1827 ; hsa-mir-4679 ; hsa-mir-383-3p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-150-3p ; hsa-mir-3941 ; hsa-mir-5690 ; hsa-mir-1228-3p ; hsa-mir-510-5p ; hsa-mir-512-5p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-5096 ; hsa-mir-197-3p ; hsa-mir-411-5p ; hsa-mir-6832-5p ; hsa-mir-6069 ; hsa-mir-6088 ; hsa-mir-4770 ; hsa-mir-4670-3p ; hsa-mir-143-3p ; hsa-mir-4794 ; hsa-mir-664a-5p ; hsa-mir-6765-3p ; hsa-mir-3149 ; hsa-mir-6083 ; hsa-mir-4321 ; hsa-mir-7846-3p ; hsa-mir-556-3p ; hsa-mir-4264 ; hsa-mir-6504-3p ; hsa-mir-548c-3p ; hsa-mir-3692-3p ; hsa-mir-4789-3p ; hsa-mir-3152-5p ; hsa-mir-4774-3p ; hsa-mir-6829-3p ; hsa-mir-6836-3p ; hsa-mir-6791-3p ; hsa-mir-6778-3p ; hsa-mir-4695-3p ; hsa-mir-4772-3p ; hsa-mir-6787-3p ; hsa-mir-1304-3p ; hsa-mir-3121-5p ; hsa-mir-6736-3p ; hsa-mir-4666a-5p ; hsa-mir-4307 ; hsa-mir-4674 ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-6881-3p ; hsa-mir-6780a-3p ; hsa-mir-7111-3p ; hsa-mir-4437 ; hsa-mir-378g ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-6742-3p ; hsa-mir-6852-5p ; hsa-mir-939-3p ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-141-5p ; hsa-mir-4298 ; hsa-mir-1302 ; hsa-mir-4425 ; hsa-mir-4703-3p ; hsa-mir-365b-5p ; hsa-mir-365a-5p ; hsa-mir-8052 ; hsa-mir-3199 ; hsa-mir-325 ; hsa-mir-4259 ; hsa-mir-4715-5p ; hsa-mir-1244 ; hsa-mir-4465 ; hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-mir-1297 ; hsa-mir-6513-3p ; hsa-mir-8062 ; hsa-mir-6818-3p ; hsa-mir-548s ; hsa-mir-4684-5p ; hsa-mir-593-3p ; hsa-mir-6895-3p ; hsa-mir-3926 ; hsa-mir-769-5p ; hsa-mir-4786-5p ; hsa-mir-3190-5p ; hsa-mir-5699-3p ; hsa-mir-4421 ; hsa-mir-339-5p ; hsa-mir-6849-3p ; hsa-mir-3613-3p ; hsa-mir-10b-5p ; hsa-mir-10a-5p ; hsa-mir-6732-3p
Nearest miRNA
hsa-mir-10397/Upstream/7452269; hsa-mir-103a-1/Downstream/2490703;
Upstream sequence
acctcagatgatccacccccttcgacctcccaaagtgttgggattacaggcatgagccacctcacctggccatattttcatttctttcaggtaaataccc
Downstream sequence
agaagtagaattgcttggtgtatggtaaatttaCAATTCATGTATTTTTACCAAGTTCAGATTTTGAATTAACATTTTCATTAGCTCTAAATTACTAATG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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