Basic Information
VIS ID
TVIS44000314
Fusion event
HTLV-1-MICD integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p22.1
Reference genome
GRCh37/hg19
Start
29938176/29970399 (Hg38)
End
29938176/29970399 (Hg38)
Orient
+
Location type
Intronic
Target gene
MICD
Nearest miRNA
hsa-mir-3143/Upstream/2822711; hsa-mir-10398/Downstream/613933;
Nearest TSS
ENST00000381078/Upstream/27845; ENST00000463275/Downstream/4713;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/13643, chr6-CpG: 66/Downstream/6226
Nearby gene
HCG9(+4716) ;
Upstream sequence
tctttcgctgttctctgggtctctgagtctattctttgggtttgaatgggtgagtttctttctcacaGGGATGTAGATGGCAACGTGGCTCTCATTCCCC
Downstream sequence
TCCCAAATACCCCAACTTTCATCGCCTGTTCCAGAAGCCTTGTCACCTACAAGCCTATCTGCACAGAAGGTATGAGGGGACCCTACAGCCCAGACAGGGA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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