Basic Information
VIS ID
TVIS44000322
Fusion event
HTLV-1-LOC105376453 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
p12.2
Reference genome
GRCh37/hg19
Start
23638187/23349258 (Hg38)
End
23638187/23349258 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105376453
Nearest miRNA
hsa-mir-1265/Upstream/1852617; hsa-mir-107/Downstream/926427;
Nearest TSS
ENST00000439456/Upstream/4413; ENST00000376495/Downstream/90200;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/5143, chr10-CpG: 236/Downstream/89649
Nearby gene
C10orf67(No orient, 4415)
Upstream sequence
CAAATAACTAATTCATGTTCTTGGGTACATAGATGCCAAGAAAGTCTTGATCTAGACAGCAAATGTGATTTTGGCTAGTGTGAATGTTCCCCTGTAGTCT
Downstream sequence
CACCTGAATAAACTGATAAAATACAGTGTTTAGAGCTGTCTACATGAGGACTAGACTCAGAGTCAAGGCATCCCCACAAGGTACCACCAAGTCACACTTT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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