Basic Information
VIS ID
TVIS44000330
Fusion event
HTLV-1-SLCO1C1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p12.2
Reference genome
GRCh37/hg19
Start
20879174/20726240 (Hg38)
End
20879174/20726240 (Hg38)
Orient
-
Location type
Intronic
Target gene
SLCO1C1
Nearest miRNA
hsa-mir-1244-3/Upstream/3052846; hsa-let-7i/Downstream/3486181;
Nearest TSS
ENST00000382841/Upstream/30490; ENST00000545880/Downstream/84462;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/173170, chr12-CpG: 34/Downstream/711295
Upstream sequence
ataaagatgaaagtatacagataaaatgcatagtaaatgcgtatatctgtcgttcaataaatattatttctCTCTTTCTTTTCTTCTTCTATTCAACCTC
Downstream sequence
TCTTTTTCTTATTTTTTTTTTTTAACTTGGGCTATGGGATAATGATCTTCCTGCAATAAAATATGAGATAGATACAAAGAAGCACATTTCCTTTGCTTCT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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