Basic Information
VIS ID
TVIS44000335
Fusion event
HTLV-1-LOC105370246 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q21.32
Reference genome
GRCh37/hg19
Start
67843484/67269352 (Hg38)
End
67843484/67269352 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA13B
Target gene
LOC105370246
Nearest miRNA
hsa-mir-1297/Upstream/1051028; hsa-mir-1267/Downstream/10428660;
Nearest TSS
ENST00000623511/Upstream/38907; ENST00000415120/Downstream/103035;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/38025, chr13-CpG: 34/Downstream/1715420
Nearby gene
PCDH9(-39016) ;
Upstream sequence
AAAAATATAGGCTGACAGAAGATTTCACATAGTCGAAAAACTAGAAAGTACCCTGAGGGTACACAGTAATCTAAATCAAAGAAAGCTGACAAAGACAAGA
Downstream sequence
TAAACAAGATAATAACAGGGTCAAAACATTCCTGTTGCCACATCTAATGaaacaaacaagcaaagaaataaaaagaaaagcagcagaaacaaacaaacaa
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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