Basic Information
VIS ID
TVIS44000347
Fusion event
HTLV-1-LOC105373719 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q24.2
Reference genome
GRCh37/hg19
Start
161959537/161103026 (Hg38)
End
161959537/161103026 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105373719
Nearest miRNA
hsa-mir-128-1/Upstream/695144; hsa-mir-10b/Downstream/7479917;
Nearest TSS
ENST00000437798/Upstream/609232; ENST00000477952/Downstream/33882;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/609166, chr2-CpG: 39/Downstream/57346
Nearby gene
TANK(+33929) ;
Upstream sequence
CATGATGAGAATTTACAGCATTCCAGAAAAAAAAAAAAAAAGCAGTGAAGCCAGATGTCAAAATATGTATTTAGTGACTCATAAAATTTCATTGCCCCAG
Downstream sequence
AGTGAAAAAAAGAAATATCACAGTTAGGCAACATTTTCAGCAGATGCCCCTAAAATACTTCTAACTTTAAAATAGTTCTTCAAATCTTCTTGAAGTGCTT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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