VISDB Viral Integration Site DataBase

VIS ID

TVIS44000381

Fusion event

HTLV-1-PLEKHA2 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr8

Cytoband

p11.22

Reference genome

Start

End

38803850/38946332 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-193a-3p ; hsa-mir-193b-3p ; hsa-mir-4795-3p ; hsa-mir-548s ; hsa-mir-374b-5p ; hsa-mir-374a-5p ; hsa-mir-3926 ; hsa-mir-590-5p ; hsa-mir-21-5p ; hsa-mir-5197-5p ; hsa-mir-34a-3p ; hsa-mir-7702 ; hsa-mir-151a-3p ; hsa-mir-155-5p ; hsa-mir-7155-3p ; hsa-mir-3136-3p ; hsa-mir-5580-5p ; hsa-mir-1287-5p ; hsa-mir-1207-3p ; hsa-mir-5685 ; hsa-mir-4690-3p ; hsa-mir-6856-3p ; hsa-mir-8485 ; hsa-mir-432-3p ; hsa-mir-1193 ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-6873-3p ; hsa-mir-514b-5p ; hsa-mir-513c-5p ; hsa-mir-6868-3p ; hsa-mir-6749-3p ; hsa-mir-942-5p ; hsa-mir-4469 ; hsa-mir-2116-3p ; hsa-mir-1248 ; hsa-mir-1237-3p ; hsa-mir-4667-3p ; hsa-mir-1470 ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-466 ; hsa-mir-4672 ; hsa-mir-3941 ; hsa-mir-3145-3p ; hsa-mir-6504-3p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-651-5p ; hsa-mir-4266 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-342-3p ; hsa-mir-1228-3p ; hsa-mir-4733-5p ; hsa-mir-4779 ; hsa-mir-4695-5p ; hsa-mir-4775 ; hsa-mir-4735-5p ; hsa-mir-590-3p ; hsa-mir-640 ; hsa-mir-1256 ; hsa-mir-6778-3p ; hsa-mir-5588-5p ; hsa-mir-4720-5p ; hsa-mir-4799-3p ; hsa-mir-150-5p ; hsa-mir-892b ; hsa-mir-6773-5p ; hsa-mir-6724-5p ; hsa-mir-296-5p

Nearest miRNA

hsa-mir-124-1/Upstream/8988984; hsa-mir-10400/Downstream/2324716;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/44470, chr8-CpG: 78/Downstream/27741

Upstream sequence

TTCTTCTGTTTTCTGGTGGTAGTAAAAGTGCCTCTTCCCAGGCTATGGCCTTGTTGGGGTTGGGGAAAACTGAGATGGCAGCGGGGACTTTCCCAGGAGC

Downstream sequence

CTGGTCTGTACCCAGTTCTCTCCCACCTCGTCTTTTTCCTTGGCTGACCAAACACAAGTTGAACTGAGAGTCTGAGTTTGAATCAAGTTCAAGGGGAAGT