Basic Information
VIS ID
TVIS44000386
Fusion event
HTLV-1-GNG12-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p31.3
Reference genome
GRCh37/hg19
Start
68648124/68182441 (Hg38)
End
68648124/68182441 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
FRA1L
Target gene
GNG12-AS1
Nearest miRNA
hsa-mir-101-1/Upstream/1553924; hsa-mir-11399/Downstream/1077;
Nearest TSS
ENST00000473358/Upstream/6064; ENST00000425820/Downstream/49246;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/18922, chr1-CpG: 83/Downstream/48484
Upstream sequence
AGGTTCCCATGCTCCTGCCAATATAACATGCTCACAACGGTCAATTCCAAAGGAAGAGCTGTCAAGAAGTGCCTGAAGATTTCCTCAAAGGGAGAGATAA
Downstream sequence
TTCATGAGCAAACAAACATCATGTCCCTAATCTTCTCTATCCTGGGGTAAACAAAATATAGTTTTCTCCCATGATTTCAGTTGCTTTCTATACCAAGTCA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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