Basic Information
VIS ID
TVIS44000397
Fusion event
HTLV-1-OR6C66P integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
55782382/55388598 (Hg38)
End
55782382/55388598 (Hg38)
Orient
+
Location type
Intronic
Target gene
OR6C66P
Nearest miRNA
hsa-mir-1244-3/Upstream/1051284; hsa-let-7i/Downstream/1805906;
Nearest TSS
ENST00000382841/Upstream/23487; ENST00000379665/Downstream/11832;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/799791, chr12-CpG: 33/Downstream/257606
Nearby gene
OR6C65(+11931) ;
Upstream sequence
CCAAAGCTAAATGTTTTGATTTTTATATTTCTATTTTTTACATATATACTGAGTATAACTGGGAACCTGACAATTATTACTCTCACTTTGATAGATGTGC
Downstream sequence
ACCTCAAAACACCCATGTACTTTTTCCTTAGGAATTTCTCTTTTCTAGAAATCTCATTCACAACAGTTTGTATTCCTAGGTTTCTGGTCAGCATCGTAAC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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