Basic Information
VIS ID
TVIS44000404
Fusion event
HTLV-1-LOC105370328 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q32.2
Reference genome
GRCh37/hg19
Start
98771593/98119339 (Hg38)
End
98771593/98119339 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA13D
Target gene
LOC105370328
Nearest miRNA
hsa-mir-1297/Upstream/1692047; hsa-mir-1267/Downstream/89185;
Nearest TSS
ENST00000623511/Upstream/99760; ENST00000600648/Downstream/23223;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/142203, chr13-CpG: 201/Downstream/22805
Nearby gene
FARP1(+23223) ;
Upstream sequence
GCTGCAGGGGCTGGTGGTCAGATTATCTCACAGATGCCCGCTGCACTGGTTCAGAGAAGGAGCAGCACAGCTGGTGCAGGCAGGGAGGTGAGGAAACACC
Downstream sequence
GAGGGAAGGGGAAGGCCAGGGAACCAGAGGTACCGGCTGGGTTCGCCACTGCTTTGCAACAGGATGGTGTTCCCCTTAGGCTGTTCTTTTTTCCTTTTCC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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