VISDB Viral Integration Site DataBase

VIS ID

TVIS44000432

Fusion event

HTLV-1-ICOSLG integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr21

Cytoband

q22.3

Reference genome

Start

End

45652558/44232675 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-766-3p ; hsa-mir-6763-5p ; hsa-mir-3150a-3p ; hsa-mir-491-5p ; hsa-mir-4792 ; hsa-mir-6825-5p ; hsa-mir-3175 ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-194-3p ; hsa-mir-1296-3p ; hsa-mir-6780a-5p ; hsa-mir-4781-5p ; hsa-mir-6799-5p ; hsa-mir-4650-3p ; hsa-mir-7106-5p ; hsa-mir-765 ; hsa-mir-7-5p ; hsa-mir-98-5p ; hsa-mir-4500 ; hsa-mir-4458 ; hsa-let-7i-5p ; hsa-let-7g-5p ; hsa-let-7f-5p ; hsa-let-7e-5p ; hsa-let-7d-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-7515 ; hsa-mir-6831-5p ; hsa-mir-3927-3p ; hsa-mir-6755-5p ; hsa-mir-4756-5p ; hsa-mir-1321 ; hsa-mir-4739 ; hsa-mir-4779 ; hsa-mir-1197 ; hsa-mir-3154 ; hsa-mir-939-5p ; hsa-mir-1343-5p ; hsa-mir-4487 ; hsa-mir-558 ; hsa-mir-3160-3p ; hsa-mir-4714-5p ; hsa-mir-146a-3p ; hsa-mir-618 ; hsa-mir-649 ; hsa-mir-490-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-6739-3p ; hsa-mir-8081 ; hsa-mir-375 ; hsa-mir-4677-5p ; hsa-mir-7156-5p ; hsa-mir-4273 ; hsa-mir-627-5p ; hsa-mir-937-5p ; hsa-mir-5193 ; hsa-mir-483-3p ; hsa-mir-129-5p ; hsa-mir-8055 ; hsa-mir-6805-3p ; hsa-mir-5691 ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-431-5p ; hsa-mir-6879-3p ; hsa-mir-4294 ; hsa-mir-3194-3p ; hsa-mir-924 ; hsa-mir-215-3p ; hsa-mir-6773-3p ; hsa-mir-500b-3p ; hsa-mir-6818-3p ; hsa-mir-4684-5p ; hsa-mir-593-3p ; hsa-mir-6895-3p ; hsa-mir-5699-3p ; hsa-mir-4421 ; hsa-mir-339-5p ; hsa-mir-4275 ; hsa-mir-4666a-3p ; hsa-mir-7851-3p ; hsa-mir-619-3p ; hsa-mir-7849-3p ; hsa-mir-548c-3p ; hsa-mir-6811-5p ; hsa-mir-6511b-5p ; hsa-mir-766-5p ; hsa-mir-671-5p ; hsa-mir-6841-3p ; hsa-mir-665 ; hsa-mir-4459 ; hsa-mir-6769a-3p ; hsa-mir-4733-3p ; hsa-mir-21-5p ; hsa-mir-1226-3p ; hsa-mir-1914-5p ; hsa-mir-197-5p ; hsa-mir-2114-5p ; hsa-mir-3132 ; hsa-mir-3667-3p ; hsa-mir-4451 ; hsa-mir-4524a-3p ; hsa-mir-4690-3p ; hsa-mir-5088-3p ; hsa-mir-5685 ; hsa-mir-6832-5p ; hsa-mir-6856-3p ; hsa-mir-6884-3p ; hsa-mir-7152-5p ; hsa-mir-3713

Nearest miRNA

hsa-let-7c/Upstream/622686; hsa-mir-6815/Downstream/1245591;

Nearest TSS

Nearest CpG islands

None/Target, chr21-CpG: 261/Upstream/30058, chr21-CpG: 19/Downstream/7644

Upstream sequence

tttttttttggtagagatgagatctcactatattgctctggttggtcttagggctcaagtgatcctcttgcctcagcctcctaagtagctgcaactatag

Downstream sequence

gtgtgcaccaccttgcccagccaaaatgagccactttatgctttatttatttatttacttttttgagacacagtcttcctctgtcgcccactctggagtg