Basic Information
VIS ID
TVIS44000450
Fusion event
HTLV-1-BBS9 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p14.3
Reference genome
GRCh37/hg19
Start
33350560/33310948 (Hg38)
End
33350560/33310948 (Hg38)
Orient
+
Location type
Intronic
Target gene
BBS9
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-4709-3p ; hsa-mir-3185 ; hsa-mir-3124-3p ; hsa-mir-676-5p ; hsa-mir-3121-5p ; hsa-mir-1264 ; hsa-mir-6875-3p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-623 ; hsa-mir-4778-3p ; hsa-mir-8067 ; hsa-mir-6508-5p ; hsa-mir-1248 ; hsa-mir-5088-3p ; hsa-mir-28-3p ; hsa-mir-8084 ; hsa-mir-5582-3p
Nearest miRNA
hsa-mir-1183/Upstream/577871; hsa-mir-10399/Downstream/1629812;
Nearest TSS
ENST00000635602/Upstream/153310; ENST00000627264/Downstream/33659;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/181317, chr7-CpG: 153/Downstream/593105
Upstream sequence
ctctatgccagccactgtgctagattctggggatatattcatgagcaaagcagtcatggtcactgaattcatggaacttgtagtgggagagaccaagatt
Downstream sequence
aaatatataattgctcaaataaacatatcattccaacagtgagaagtactgtgaaggaatagtagctggcactttgggagcatataacaggggacctggc
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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